Methotrexate (Rheumatrex) is used to treat rheumatoid arthritis, severe psoriasis, and certain types of cancer.

Founded in 1901, Teva Pharmaceuticals is the world's largest generic manufacturer with a total of 550 drugs. Its largest markets are in the UK, Germany, and the U.S but is in a top three leadership position in over 25 markets. Teva has 70 manufacturing sites including the U.S. and Israel.